Invitrogen Anti-SATB2 Monoclonal (CL0276), Catalog # MA5-31339. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications.

2021-03-28 · Results: SATB2 single stain showed a good sensitivity of 83% and the highest specificity of 78% for AMNs over OMNs among all four stains. DS with SATB2 and villin showed an identical sensitivity of 78% but specificity increased to 94%, while DS with SATB2 and CK20 showed a sensitivity of 80% and a specificity of 100%.

24 hours. *The CPT codes provided with our test descriptions Feb 25, 2021 SATB2 is a biomarker for colorectal cancer, 85% of all CRC patients are positive for SATB2 and other cancer types rarely display SATB2 Anti-SATB2 Antibody (SATBA4B10): sc-81376 · Can I use this mouse monoclonal antibody for immunohistochemical staining of mouse tissue? · What is the Immunofluorescence staining of U-138 MG cells using the Anti-SATB2 monoclonal antibody, showing specific staining in the nucleoplasm in green. Microtubule- (I) Representative immunofluorescence staining figure for the SATB2 and SOX2 to illustrate that SATB2+ cells are mainly located above the SOX2+ progenitor mucin; PD-L1; SATB2; special stain.

The malignancy expression profile of SATB2 was initially characterized using a tissue microarray of 216 malignancy samples designed to represent the 20 most common human malignancies. 3 Colorectal adenocarcinoma showed strong expression of SATB2 in the majority of samples, and strong expression was also seen in 1 renal cell carcinoma. 3 Weak to moderate SATB2 expression was also seen in sinonasal carcinomas (56%; 5 of 9) and a small percentage of ovarian, breast, lung, and urothelial 2018-02-01 · Recent studies have shown that SATB2 could serve as a clinically useful diagnostic marker for CRCs (Dragomir et al., 2014, Kim et al., 2016, Lin et al., 2014, Magnusson et al., 2011, Ordonez, 2014) as 71–97% of primary and metastatic CRCs have been reported to stain positively for SATB2 expression (Dragomir et al., 2014, Eberhard et al., 2012 Request PDF | Dual Immunostain With SATB2 and CK20 Differentiates Appendiceal Mucinous Neoplasms From Ovarian Mucinous Neoplasms | Objectives: Determination of the primary site of origin for Special AT-rich sequence binding protein 2 (SATB2) is a 733–amino acid human DNA-binding protein involved in transcriptional regulation and chromatin remodeling, and its expression is restricted to glandular cells lining the lower GI tract. 22 A recent study demonstrated that SATB2 is a sensitive and highly specific marker for colorectal carcinoma (CRC) with distinct positivity in 85% of all CRCs, and SATB2 in combination with CK20 can identify 97% of CRCs. 23 The same study also revealed stain SATB2 in epithelial cells of the appendix and neoplastic cells of the colon adenocarcinoma (tissue core 5), whereas demonstration of SATB2 in germ cells (primarily spermatocytes) in seminiferous tubules of the testis and neoplastic cells of the neuroendocrine tumour and colon adenocarcinoma (tissue core 4) SATB2 controls multiple processes required for the formation of intracortical circuits that may be relevant to ASD (Fig. 6.3).

Focal (<5%) SATB2 staining was noted in 3 additional tumors. Conclusion: SATB2 is a novel marker that is highly specific for colorectal adenocarcinomas Jun 25, 2019 All cases were assessed for SATB2, PAX8 CK7, CK20, and CDX2 expression The staining intensity of SATB2 was generally strong with only Invitrogen Anti-SATB2 Monoclonal (CL0276), Catalog # MA5-31339. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications.

SATB2 also regulates skeletal development, osteoblast differentiation, and modulates immunoglobulin expression. In normal tissues, strong nuclear SATB2 expression is observed in essentially all glandular cells lining the lower gastrointestinal tract, including the appendix, colon, and rectum. SATB2 is also

SATB2: SATB2 IHC, Tech Only: For each additional technical component only IHC stain performed, an additional bill-only test ID will be reflexed and charged (IHTOA). Forms. If not ordering electronically, complete, print, and send a Immunohistochemical (IHC)/In Situ Hybridization (ISH) Stains Request (T763) with the specimen.

Expression of SATB2 (FLJ21474, KIAA1034) in lymph node tissue. Antibody staining with HPA001042, HPA029543, CAB023669, CAB062562, CAB067751, CAB068229, CAB068230 and CAB068231 in immunohistochemistry. Complete information for SATB2 gene (Protein Coding), SATB Homeobox 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium Triple Stain PSA PSAP/HPAPMLH1 PSMA PTH RCC1 S100 ESCC (Esophageal) S100p SALL4 SATB2(PASD+PAS) Serotonin. Reticulin SF1 SMA SMMHC Smoothelin Somatostatin SSTR2 (Somatostatin Receptor, Type 2) SOX2 SOX10 SOX11 STAT6 Surfactant TCL1 TCR BetaF1 TCR Delta Thrombomodulin (TM) Thyroglobulin (TGB) TIA1 Test Code SATB2 SATB2 Immunostain, Technical Component Only Advisory Information This test includes only technical performance of the stain (no pathologist interpretation is performed). Immunohistochemistry and special stains play an increasingly important role in gastrointestinal pathology practice. In neoplastic disorders they are used to confirm the diagnosis, identify prognostic/predictive features, and screen for an underlying genetic syndrome.

This product, sc-81376, is recommended for immunostaining Immunofluorescence staining of U-138 MG cells using the Anti-SATB2 monoclonal antibody, showing specific staining in the nucleoplasm in green. Microtubule- First panel: typical staining pattern for an ovarian mucinous carcinoma: Hematoxylin and eosin (H&E) stain, CK7 diffuse, SATB2 absent, PAX8 nondiffuse , CDX2 mucin; PD-L1; SATB2; special stain. Introduction. Immunohistochemistry (IHC) and special stains are indispens- able adjuncts in the reporting of gastrointestinal (I) Representative immunofluorescence staining figure for the SATB2 and SOX2 to illustrate that SATB2+ cells are mainly located above the SOX2+ progenitor Dec 20, 2019 SATB2 restrains induction of muscle cell differentiation. Western (B) Representative immunofluorescent staining of SATB2 in proliferating and Feb 2, 2021 Cytoskeletal staining of zebrafish melanoma in vitro cultures (Zmel1 MCR:EGFP and 45–3 MCR:SATB2) with phalloidin revealed the presence Anti-SATB2 antibody produced in rabbit (Anti-APXL3 ); Prestige Antibodies to be used according to the standard IHC staining protocol described below. Sep 8, 2020 SATB2-associated syndrome is a condition that affects several body systems. Explore symptoms, inheritance, genetics of this condition.
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The data generated indicate that the rabbit monoclonal anti-SATB2 has a sensitivity of 95.5% and a specificity of 85%.6 Medullary carcinoma (MC) of the colon and rectum is a rare, distinct variant of colorectal carcinoma, first described nearly 2 decades ago. 2017-10-01 SATB2 and TLE1 Expression in BCOR-CCNB3 (Ewing-like) Sarcoma, Mimicking Small Cell Osteosarcoma and Poorly Differentiated Synovial Sarcoma Creytens, David MD, PhD *,† Author Information Results: SATB2 single stain showed a good sensitivity of 83% and the highest specificity of 78% for AMNs over OMNs among all four stains. DS with SATB2 and villin showed an identical sensitivity This test includes only technical performance of the stain SATB2 IHC, Tech Only: Bill only; no result: Forms.

SATB2 is a Promising Biomarker for Identifying a Colorectal Origin for Liver Metastatic Adenocarcinomas. Yi-Jun Zhang et al.
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Focal weak staining was identified in one (9%) unclassified pleomorphic sarcoma and one (13%) monophasic synovial sarcoma. SATB2 was negative in all soft tissue tumours with prominent sclerotic stromal collagen. Conclusions: SATB2 is a marker of osteoblastic differentiation in benign and malignant mesenchymal tumours. Although SATB2 is not specific for osteosarcoma, it has the potential to be a useful adjunct in some settings, particularly in the distinction between hyalinized collagen and

In total, 10% was Nov 3, 2020 4,7 SATB2 staining in colorectal adenocarcinoma has shown a have been reported to stain positively for SATB2 expression (Dragomir et al., utility of Special AT-rich sequence binding protein-2 (SATB2) in determining the primary site. were stained for SATB2, Islet1, PAX6, TTF1, and CDX2. (1%). Focal (<5%) SATB2 staining was noted in 3 additional tumors. Conclusion: SATB2 is a novel marker that is highly specific for colorectal adenocarcinomas Jun 25, 2019 All cases were assessed for SATB2, PAX8 CK7, CK20, and CDX2 expression The staining intensity of SATB2 was generally strong with only Invitrogen Anti-SATB2 Monoclonal (CL0276), Catalog # MA5-31339.

In their immunohistochemical study of 30 consecutive cases of invasive ductal breast adenocarcinoma, 6 cases (20%) showed weak (1+) staining for SATB2 in

Focal (<5%) SATB2 staining was noted in 3 additional tumors. Conclusion: SATB2 is a novel marker that is highly specific for colorectal adenocarcinomas Invitrogen Anti-SATB2 Monoclonal (CL0276), Catalog # MA5-31339. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. Jun 25, 2019 All cases were assessed for SATB2, PAX8 CK7, CK20, and CDX2 expression The staining intensity of SATB2 was generally strong with only SATB2 stains colonic and osteogenic cells and their neoplasms. Stain Only.

It may also be used to differentiate rectal neuroendocrine tumors from other neuroendocrine tumors of the gastrointestinal tract. SATB2 stains colonic and osteogenic cells and their neoplasms. Specimen Requirements A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type Expression of SATB2 (FLJ21474, KIAA1034) in cerebral cortex tissue.